Post by jackson03 on Feb 18, 2019 5:08:55 GMT -4
Zebrafish Toxicity assay is a member of the family of carp fish. Zebrafish is a model organism to study the development of vertebrates. In this sense, zebrafish is useful because the embryo is transparent, it develops out of its mother, and its development from egg to larva occurs in only three days.
Basic biomedical research is a necessity in the field of health, as many substances and procedures are evaluated to guarantee the benefit of patients, in whom they will finally be employed. However, there are limitations in our countries for this type of research, due to the high investment it demands, especially due to the infrastructure and care that traditional animal models used require, which must meet specific bioethical standards. Having a low cost animal model and high versatility can promote preclinical research especially in the anesthesiology field. Zebrafish is an emerging animal model with many qualities that position it as an attractive alternative to carry out basic biomedical research: it has high fertility, it has rapid development from the embryo stage to adult and the cost of infrastructure, inputs and reagents Necessary for breeding and reproduction are low. The present work is a narrative review that shows studies that have employed fish for drug research and anesthesia protocols. Likewise, the general characteristics of the zebrafish and some basic research work in the field of anesthesiology are presented in which it has been used as an experimenting animal. This information may be useful for professionals and researchers in the field of anesthesiology interested in performing basic biomedical research with zebrafish as a model of study.
Basic biomedical research is a necessity in the field of health, as many substances and procedures are evaluated to guarantee the benefit of patients, in whom they will finally be employed. However, there are limitations in our countries for this type of research, due to the high investment it demands, especially due to the infrastructure and care that traditional animal models used require, which must meet specific bioethical standards. Having a low cost animal model and high versatility can promote preclinical research especially in the anesthesiology field. Zebrafish is an emerging animal model with many qualities that position it as an attractive alternative to carry out basic biomedical research: it has high fertility, it has rapid development from the embryo stage to adult and the cost of infrastructure, inputs and reagents Necessary for breeding and reproduction are low. The present work is a narrative review that shows studies that have employed fish for drug research and anesthesia protocols. Likewise, the general characteristics of the zebrafish and some basic research work in the field of anesthesiology are presented in which it has been used as an experimenting animal. This information may be useful for professionals and researchers in the field of anesthesiology interested in performing basic biomedical research with zebrafish as a model of study.